Products產品資訊
  1. Home
  2. 產品資訊

  1. 細胞代謝活化修護促進劑

細胞代謝活化修護促進劑

商品詳細說明

細胞代謝活化修護促進劑HMWYN01

(Cell metabolism activator and repair promoter HMWYN01)

 

HMWYN01的特性

  1. 增強細胞代謝：HMWYN01可以增強細胞代謝活性，有助於細胞生長與功能。
  2. 抗發炎作用：HMWYN01具有抑制發炎反應的能力，減少細胞對發炎刺激的反應。
  3. 保護特性：當暴露於外部刺激或損傷時，HMWYN01可以保護細胞免受進一步的傷害，有助於維持細胞的健康和完整性。
  4. 促進膠原蛋白合成：HMWYN01 有助於增加膠原蛋白合成，這對於組織修復和再生過程至關重要。
  5. 加速傷口癒合：HMWYN01 促進傷口加速癒合，包括切口和其他形式的皮膚損傷。

總體而言，HMWYN01 是一種多功能生物活性物質，具有促進細胞健康和組織修復的潛力。
 

Characteristics of HMWYN01

  1. Enhanced Cell Metabolism: HMWYN01 can boost cellular metabolic activity, aiding in cell growth and functionality.
  2. Anti-inflammatory Effect: HMWYN01 possesses the ability to suppress inflammatory responses, reducing cellular reactions to inflammation stimuli.
  3. Protective Properties: When exposed to external stimuli or damage, HMWYN01 can shield cells from further harm, helping to maintain cellular health and integrity.
  4. Promotion of Collagen Synthesis: HMWYN01 contributes to increased collagen synthesis, crucial for tissue repair and regeneration processes.
  5. Accelerated Wound Healing: HMWYN01 facilitates the expedited healing of wounds, including incisions and other forms of skin damage.

Overall, HMWYN01 is a multifunctional bioactive substance with the potential to promote cellular health and tissue repair.



  1.本部份檢測證明HMWYN01所使用的原料不含有包括砷、鉛、汞與鎘等四大重金屬。
This test section demonstrates that the raw materials used in HMWYN01 do not contain the four major heavy metals, including arsenic, lead, mercury, and cadmium.





2.本部份檢測經由國際標準組織 (International Organization for Standardization，簡稱：ISO)的體外細胞毒性試驗(ISO 10993-5)證明HMWYN01對細胞並無造成細胞毒性，可視為一安全的物質。
This section of testing, conducted through the International Organization for Standardization (ISO) in vitro cytotoxicity assay (ISO 10993-5), demonstrates that HMWYN01 does not induce cytotoxicity in cells, thus indicating its safety as a substance.



3.本部份實驗證實HMWYN01對於測試細胞RAW264.7受到細菌脂多醣(LPS)發炎反應刺激後能夠有效降低一氧化氮與細胞激素IL-6的生成量，亦即HMWYN01具有抗發炎的效果。
This section of the experiment confirms that HMWYN01 effectively reduces the production of nitric oxide and the cytokine IL-6 in RAW264.7 cells stimulated by bacterial lipopolysaccharide (LPS) inflammation response. Therefore, HMWYN01 demonstrates anti-inflammatory effects.



4.細胞活力是指一個細胞群體中健康的活細胞所占的比例，細胞的活力可藉由測定持續進行中的代謝活動和酵素活性等細胞生理活動來評估。本試驗證明HMWYN01具有提高皮膚纖維母細  胞代謝活力的能力。
Cell viability refers to the proportion of healthy, living cells within a cell population. Cell viability can be assessed by measuring ongoing metabolic activity and enzyme function, among other cellular physiological activities. This experiment demonstrates that HMWYN01 has the ability to enhance the metabolic activity of dermal fibroblasts.



5.本試驗顯示HMWYN01與市售產品比較後發現HMWYN01促進皮膚纖維母細胞代謝活力的能力顯著高於競爭產品。
This experiment shows that HMWYN01 exhibits significantly higher capability in promoting the metabolic activity of dermal fibroblasts compared to competing products on the market.



6.紫外線很容易引起皮膚急性的傷害-例如曬傷(sunburn)，且具有累積作用，因此長期曝曬會造成皮膚包括色素沉澱、老化及皮膚癌。在本試驗中我們採用波長312nm的UVB對皮膚纖維母細胞進行照射以模擬細胞曝露於UVB時所造成的傷害，並比較各組別包括無加藥保護的細胞UVB曝露控制組(Control)、添加HMWYN01保護的細胞UVB曝露控制組(HMWYN01)與添加已知具有保護細胞免受到UVB曝露的NAC藥品組(NAC)對於細胞活性有無差異之影響。我們發現添加HMWYN01可有效降低UVB對皮膚纖維母細胞的傷害且達到統計上的顯著差異，亦即HMWYN01對經由UVB暴露之纖維母細胞具有保護作用。
UV radiation can easily cause acute skin damage, such as sunburn, and has cumulative effects, leading to long-term skin issues including pigmentation, aging, and skin cancer. In this experiment, we irradiated dermal fibroblasts with UVB radiation at a wavelength of 312nm to simulate the damage caused by UVB exposure to cells. We compared different groups including cells without any protective treatment exposed to UVB (Control), cells treated with HMWYN01 for protection against UVB exposure (HMWYN01), and cells treated with NAC, a known protective agent against UVB exposure (NAC), to assess their impact on cell viability. We found that adding HMWYN01 effectively reduced UVB-induced damage to dermal fibroblasts, with statistically significant differences observed. This indicates that HMWYN01 has a protective effect on fibroblasts exposed to UVB radiation.



7.膠原蛋白因其特殊的多胜肽結構，對於人體各組織間扮演類似骨架的角色以提供支撐、彈性與延展。傷口癒合過程中創傷部位需要大量膠原蛋白來填充及修護組織以促進傷口癒合，在本試驗中我們以HMWN01添加至生長培養基測試其對皮膚纖維母細胞是否會對膠原蛋白之分泌量有所影響。本部份的試驗結果顯示控制組於培養0小時至48小時候膠原蛋白累積量由42.6±23.9µg/mL顯著下降至21.4±6.9µg/mL(p=0.0148);相對的，有添加HMWYN01的試驗組於培養0小時至48小時候膠原蛋白累積量由48.4±28.8µg/mL僅微幅下降至44.3±11.4µg/mL(p=0.6805)，並無達到統計上之顯著差異。因此本試驗證明HMWYN01具有調節膠原蛋白含量的特性。
The results of this section of the experiment showed that in the control group, the accumulation of collagen decreased significantly from 42.6±23.9 µg/mL at 0 hours to 21.4±6.9 µg/mL at 48 hours (p=0.0148). In contrast, the experimental group with HMWYN01 added showed a slight decrease in collagen accumulation from 48.4±28.8 µg/mL at 0 hours to 44.3±11.4 µg/mL at 48 hours (p=0.6805), with no statistically significant difference observed. Therefore, this experiment demonstrates that HMWYN01 has the characteristic of modulating collagen content.



8.為了瞭解HMWYN01對於促進纖維母細胞傷口癒合的效果，我們進行了傷口癒合試驗(Wound Healing assay)。在本試驗中我們發現有添加HMWYN01的試驗組與無添加HMWYN01的控制組在24小時的傷口癒合速度上存在統計上的顯著差異，且高濃度的HMWYN01-H與低濃度的HMWYN01-L在傷口癒合的速度亦具有統計上的差異，亦即HMWYN01對於傷口的癒合具有明確的濃度效應。因此，本項實驗證明HMWYN01具有促進傷口快速癒合的功能。
To understand the effect of HMWYN01 on promoting wound healing in dermal fibroblasts, we conducted a Wound Healing assay. In this experiment, we found a statistically significant difference in the wound healing rate at 24 hours between the experimental group with added HMWYN01 and the control group without HMWYN01. Additionally, there was a statistical difference in the wound healing rate between the high concentration HMWYN01-H and low concentration HMWYN01-L groups, indicating a concentration-dependent effect of HMWYN01 on wound healing. Therefore, this experiment demonstrates that HMWYN01 has the capability to promote rapid wound healing.



9.為了評估HMWYN01對於實際皮膚切割傷的傷口癒合效果，我們進行了老鼠離體傷口癒合試驗。在本試驗中我們發現添加塗抹HMWYN01於受測老鼠皮膚的切割傷試驗組(HMWYN01)與無添加HMWYN01於受測老鼠皮膚的控制組(Control)從第九天、第十二天、第十六天與第二十天時傷口癒合的速度具有明顯的統計差異。因此綜合in vitro與in vivo的試驗結果，本實驗證明HMWYN01具有促進傷口快速癒合的功能。
To evaluate the wound healing effect of HMWYN01 on actual skin cut wounds, we conducted an ex vivo wound healing assay on mice. In this experiment, we observed a significant statistical difference in the wound healing rate between the test group (HMWYN01) where HMWYN01 was applied topically to the cut wounds on the skin of the mice, and the control group (Control) where HMWYN01 was not applied, on the ninth, twelfth, sixteenth, and twentieth days. Therefore, based on the results from both in vitro and in vivo experiments, this study demonstrates that HMWYN01 has the ability to promote rapid wound healing.



10.傷口癒合是一連串複雜的過程，其過程會牽涉细胞移行、肉芽組織的形成、血菅新生以及基質的重塑均有賴於细胞外基質的調控。本試驗發現無使用HMWYN01塗抹於控制組切割傷部位與使用HMWYN01塗抹於試驗組切割傷部位對於組織受到傷害後的再上皮化(Re-epithelializtion)、炎症反應(Inflammation)與血管新生(Angiogenesis)具有差異。此一結果證明HWYN01對於促進皮膚傷口癒合與品質具有明確的效果。

Wound healing is a complex process involving cell migration, granulation tissue formation, angiogenesis, and extracellular matrix remodeling, all of which depend on the regulation of the extracellular matrix. This experiment found differences in re-epithelialization, inflammation, and angiogenesis between the control group where HMWYN01 was not applied to the cut wounds and the test group where HMWYN01 was applied to the cut wounds. This result demonstrates that HWYN01 has a clear effect on promoting skin wound healing and quality.

BACK